BM14 is one of the bending magnet beamlines of the European Synchrotron Radiation Facility (ESRF) for Macromolecular Crystallography (MX) experiments. The optical design is suited to the rapid and accurate wavelength changes required for the MAD / SAD techniques. It is tunable over a wavelength range of 0.7 – 1.8 Å and has a standard working energy of 0.976 Å or 12.7 keV.
Beamline features include:
- EMBL-ESRF Robotic Sample Changer (SC3)
- MD2 Microdiffractometer (EMBL-Maatel)
- Automated Sample Cantering (MxCube)
- Mini-Kappa goniometer for crystal reorientation
- MarCCD detector (active area of 225 x 225 mm)
- Cryo-cooling System (Oxford 700 Cryostream)
- Fluorescence Detector (Roentec)
- Remotely controlled Cryostream-shutter for flash-annealing
- Humidity Controlled Device for crystal dehydration (HC1)
- Remotely Accessible Beamline
- Oxygen Pressurised Crystallography
- Sulphur SAD/MAD
- Crystallisation plate screening (currently being installed)
BM14 provides beamtime services and training to structural biologist from INDIA [via Department of Biotechnology (DBT) funding] and EUROPE [via European Molecular Biology Laboratory (EMBL) and European Synchrotron Radiation Source (ESRF) funding] on the basis of peer-reviewed beamtime proposals (www.bm14.eu). BM14 beamline scientists collaborate with a number of scientific research groups to determine novel crystal structures of biotechnological and biomedical interest.